Click here for a larger version of the wide angle picture of the NMR bay at the CCRC (2.1 MB)
 About SECNMR Contact Us
Nuclear Magnetic Resonance (NMR) provides a means of investigating the structure and dynamics of biologically important macromolecules without the necessity of crystallization. This is important for the investigation of biomolecule function in an environment as close as possible to physiological conditions. Such investigations can be important stepping-stones to the understanding of disease processes and the design of agents that can combat disease. Application of NMR has, however, been restricted to smaller systems by the lack of resolution, sensitivity, and appropriate measurable parameters. Higher fields, and new experiments that exploit these fields, can greatly extend applicability of NMR based research.

The Southeast Collaboratory for Biomolecular NMR (SECNMR) was established in July of 2002 by the National Institute of General Medical Sciences and the Georgia Research Alliance to provide for sharing of both equipment and ideas among an initial group of researchers from 17 institutions in the Southeast region of the country. The centerpiece of the facility is an instrument that operates with a magnetic field of 21.1T. This corresponds to a proton NMR operating frequency equal to 900 MHz. The 900 is backed up with 800 MHz and 600 MHz instruments all with high sensitivity cryo-probes. The productivity is enhanced by computational and internet communication resources that allow remote use and broad sharing of resulting developments. In 2007 the facility became self supporting via user fees. However it remains open to use by all scientists having needs for its unique capabilities. The staff operating the facility has particular experience with protein and carbohydrate solution NMR, metabolomics and oriented sample techniques. Links to other resources at the CCRC and UGA can provide access to small animal imaging and hyperpolarization for in vitro metabolic studies.

facility maintained at:

The Complex Carbohydrate
Research Center		 The University of Georgia
UGA		 Funding Provided By:
National Institute of
General Medical Sciences
&		  
The Georgia Research Alliance